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008			150219s2015 xxk||||| 00| ||eng c
016	7		_aGBB4C5637 _2UK
016	7		_a016938745 _2DE-101
020			_a9780198726326 _cpbk. : £39.99 _9978-0-19-872632-6
024	3		_a9780198726326
035			_a(DE-D210)CP000008128
035			_a(DE-576)42631610X
035			_a(DE-627)818598824
035			_a(DE-599)BSZ42631610X
035			_a(OCoLC)1411779302
035			_a(BL)016938745
040			_aDE-627 _bger _cDE-627 _erakwb
041			_aeng
044			_cXA-GB
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050		0	_aQP551
076	c		_adruck
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084			_aUQ 1000 _qBSZ _2rvk _0(DE-625)rvk/146467:
084			_a38.31 _2bkl
100	1		_aSherwood, Dennis _d1949- _0(DE-588)128479302 _0(DE-627)373390483 _0(DE-576)297169424 _4aut _94521
245	1	0	_aCrystals, x-rays and proteins _bcomprehensive protein crystallography _cby Dennis Sherwood ; Jon Cooper
250			_a1. publ. in paperb.
264		1	_aOxford _bOxford University Press _c2015
300			_aXVII, 625 S _billustrations (black and white) _c25 cm
336			_aText _btxt _2rdacontent
337			_aohne Hilfsmittel zu benutzen _bn _2rdamedia
338			_aBand _bnc _2rdacarrier
500			_aLiteraturverz. S. 497 - 505
520			_a"A complete account of the theory of the diffraction of x-rays by crystals with particular reference to the processes of determining the structures of protein molecules, this book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including:- The practical aspects of sample preparation and x-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels- The important role played by the Patterson function in structure analysis by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods which reveal further detail of great functional importance in a crystal structure"--
650		0	_aCrystallography
650		0	_aProteins _xStructure
650		0	_aX-rays _xDiffraction
650		0	_aProteins _xAnalysis
650		0	_aX-ray crystallography
689	0	0	_Ds _0(DE-588)4033217-2 _0(DE-627)106258443 _0(DE-576)209000651 _aKristallographie _2gnd
689	0		_5(DE-627)
689	1	0	_Ds _0(DE-588)4178310-4 _0(DE-627)105342440 _0(DE-576)209983531 _aRöntgenkristallographie _2gnd
689	1		_5(DE-627)
700	1		_aCooper, Jonathan B. _0(DE-588)142837768 _0(DE-627)704322722 _0(DE-576)333640764 _4aut _96359
935			_iBlocktest
936	r	v	_aUQ 1000 _bLehrbücher der Kristallographie und Mineralogie _kPhysik _kKristallographie _kLehrbücher der Kristallographie und Mineralogie _0(DE-627)127114364X _0(DE-625)rvk/146467: _0(DE-576)20114364X
936	b	k	_a38.31 _jKristallographie _0(DE-627)181570114
942			_cSONST
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